Our novel fragment library has been designed to be redly amenable to medicinal chemistry optimization.
The optimized fragments at one end which is amenable to further derivatization
The small number of analogs around each functional group allows us to perform Structure-Activity Relationship (SAR) around the key pharmacophore
The structural links between the fragment collections allow some rapid SAR
Our approach involves optimizing fragments at one end, creating a platform that is highly amenable to further derivatization. This strategic optimization enhances the flexibility of our compounds, opening avenues for customization and refinement.
